Evaluation of mucosal B cell response to PEDV in infected sows
Porcine epidemic diarrhea virus (PEDV) has rapidly become one of the most economically devastating enteric diseases in the US swine industry. The virus is most severe in neonatal pigs with mortality up to 100%. Thus, induction of strong maternal immunity…
Development of PRRS virus-like-particles containing nanoparticle vaccine and its evaluation in pigs
Porcine Reproductive and Respiratory Syndrome (PRRS) is a chronic and economically important viral disease of pigs. Currently used PRRS virus (PRRSV) vaccines have failed to completely protect against reinfections. In addition, reports of live virus vaccine acting as a source…
Development of novel mucosal vaccines for the control of PRRSV outbreaks
Porcine Reproductive and Respiratory Syndrome (PRRS) is an economically important chronic viral disease of pigs. Available PRRS virus (PRRSV) vaccines are not completely protective to control the disease outbreaks. Conventional PRRSV vaccines administered by intramuscular injection reduced the persistence and…
Evaluation of adjuvants at the mucosal area for the development of innovative mucosal vaccine against PRRS
Porcine Reproductive and Respiratory Syndrome (PRRS) is a chronic and economically important viral disease of pigs. Currently available PRRS virus (PRRSV) vaccines have been administered systemically (intramuscular injection) and they failed to completely protect against reinfections, and absolutely no protection…