An efficacious corn-based nanoparticle influenza vaccine for pigs
Comparative pathogenesis of different porcine rotavirus C (RVC) genotypes and correlation between maternal immune status and RVC diarrhea prevalence in suckling piglets
Evaluation of mucosal B cell response to PEDV in infected sows
Porcine epidemic diarrhea virus (PEDV) has rapidly become one of the most economically devastating enteric diseases in the US swine industry. The virus is most severe in neonatal pigs with mortality up to 100%. Thus, induction of strong maternal immunity…
Genogroup A, B and C porcine rotaviruses: Prevalence and implications for effective vaccines
Our study provides critical information on high genetic and antigenic diversity of porcine RVs (PRVs) confirming that the existing PRV vaccines do not include dominant field PRV strains currently circulating in the US. In particular, we have demonstrated that the…
The effect of disinfection practices on RT-PCR detection of PEDv
Porcine epidemic diarrhea virus (PEDV) is causing significant damage to the United States pork industry. Rapid dissemination of this highly contagious virus across the nation has occurred, likely via contaminated transportation equipment. Cleaning and disinfection of trucks and trailers is…
Development of PRRS virus-like-particles containing nanoparticle vaccine and its evaluation in pigs
Porcine Reproductive and Respiratory Syndrome (PRRS) is a chronic and economically important viral disease of pigs. Currently used PRRS virus (PRRSV) vaccines have failed to completely protect against reinfections. In addition, reports of live virus vaccine acting as a source…
Monitoring of Antimicrobial Resistance in Food Animal Production: Partnership between National Antimicrobial resistance Monitoring System (NARMS) and Academia
Collaborative partners including four Universities (Ohio State, Minnesota, North Carolina State and Iowa State), industry and federal agency (USDA) conducted a one year on-farm monitoring project in swine production systems focusing on four major swine producing states: Iowa, North Carolina,…
Phenotypic and Genotypic Characterization of Methicillin Susceptible Staphylococcus aureus (MSSA) in Pigs and Farm Workers
This study was conducted to characterize specific bacteria known as methicillin susceptible Staphylococcus aureus (MSSA) isolated from pigs and farm workers. The antimicrobial susceptibilities of the isolates were determined using the broth dilution method and the relatedness of isolates using…
Impact of ceftiofur use on the dissemination of resistant enteric bacteria in finishing swine populations
The antibiotics Exceed and Excenel are two formulations of the cephalosporin drug ceftiofur that are commonly used to treat finishing pigs in the US. Our object was to understand the relationship between the use of ceftiofur and the spread of…